Nhat Le
Contact Information
Research Assistant Professor, Department of Cancer Biology & Genetics
She/Her
Areas of Expertise
- Molecular and Celular Neuroscience
- Neurotrauma, Neurological Disorders, and Gene/Clinical Therapies
- Neuro-Oncology
Our study seeks to define the mechanistic basis for how protein-based endogenous substances initiate disease signaling pathways and to develop therapeutic modalities for the elimination of these neurotoxic substances in human disease conditions. We currently focus on cancers and neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and Parkinson’s diseases.
Our team performs new platform technologies that uniquely combine induced pluripotent stem cell (iPSC)-derived human disease models, and designed protein-based biological/therapeutic tools to meet the effective and thorough applying cutting-edge biochemical and cell biological techniques. We have established highly multidisciplinary collaborations at OSU, including both research and clinical experts in protein biochemistry, enzymology, protein/peptide delivery methodology, mass spec, electrophysiology, and neurology.