Warren “Alex” Campbell, MD, PhD. Graduated NGP 2022

Current position: Resident, Interventional Radiology, University of Virginia

“Chromatin access regulates the formation of Müller glia-derived progenitor cells in the retina”  Glia  2023. 

Combining single cell RNA-seq and single cell ATAC-seq to identify how inhibition of histone methylation increases chromatin access and changes patterns of gene expression at single cell resolution. We show that suppressed chromatin access of pro-glial gene networks is required to permit the reprogramming of Müller glia into proliferating progenitor-like cells in the retina.

Link to full length paper